Roxana Wasnick  MD PhD
Flow cytometry & Lung research  consulting
Transformational science coach 

              

                                             https://www.linkedin.com/in/roxana-wasnick-5b9b567/
             

 

Creative problem solver and continuous learner, I am always interested in new technologies and concepts in biology and medicine. My solid scientific upbringing in the field of lung stem cells and regenerative medicine, backed by profound medical knowledge provide a wide understanding of mechanistic and therapeutic aspects of human body in health and disease. An avid explorer of human connection, I believe that effective communication and freedom of expression are essential for any collective  endeavor - family, classroom or business. 

 

     Work experience

2020

2004-2020

2004-2009

2007-2009

CureVac, Tubingen, Germany - Scientist

University of Giessen , Giessen, Germany - Postdoc

Ecole Polytechnique Federale de Lausanne, Switzerland - Postdoc

Duke University, Durham, USA - Visiting grad student

     Education

2003-2009

PhD, University of Pittsburgh School of Medicine, Pittsburgh, USA

1996-2002

Medical Doctor, Universitatea de Medicina si Farmacie Iuliu Hatieganu, Cluj-Napoca, Romania

                                          Publication list

 

  1. Ahmadvand N, Carraro G, Jones MR, Shalashova I, Noori A, Wilhelm J, Baal N, Khosravi F, Chen C, Zhang J-S, Ruppert C, Guenther A, Wasnick RM*, Bellusci S*. Cell-Surface Programmed Death Ligand-1 Expression Identifies a Sub-Population of Distal Epithelial Cells Enriched in Idiopathic Pulmonary Fibrosis. Cells. 2022; 11(10):1593. https://doi.org/10.3390/cells11101593
  2. Wasnick RM, Shalashova I, Wilhelm J, Khadim A, Schmidt N, Hackstein H, Hecker A, Hoetzenecker K, Seeger W, Bellusci S, El Agha E, Ruppert C, Guenther A. Differential LysoTracker Uptake Defines Two Populations of Distal Epithelial Cells in Idiopathic Pulmonary Fibrosis. Cells. 2022; 11(2):235. https://doi.org/10.3390/cells11020235
  3. Wasnick R, Korfei M, Piskulak K, Henneke I, Wilhelm J, Mahavadi P, von der Beck D, Koch M, Shalashova I, Klymenko O, Fink L, Witt H, Hackstein H, El Agha E, Bellusci S, Klepetko W, Königshoff M, Eickelberg O, Braun T, Seeger W, Ruppert C, Günther A, Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition; submitted manuscript (https://www.biorxiv.org/content/10.1101/580498v2)
  4. Zehendner CM, Valasarajan C, Werner A, Boeckel JN, Bischoff FC, John D, Weirick T, Glaser SF, Rossbach O, Jaé N, Demolli S, Khassafi F, Yuan K, de Jesus Perez VA, Michalik KM, Chen W, Seeger W, Guenther A, Wasnick RM, Uchida S, Zeiher AM, Dimmeler S, Pullamsetti SS. Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ; Am J Respir Crit Care Med. 2020 Nov 15;202(10):1445-1457
  5. Ahmadvand N, Khosravi F, Lingampally A, Wasnick R, Vazquez-Armendariz I, Heiner M, Rivetti S, Lv Qingyu, Wilhelm J, Gunther A, Herold, S, Chen C, Minoo, P, Zhang JS, Bellusci S.  Identification in human and mouse of a novel population of AT2 progenitor cells necessary for alveolar repair; Eur Respir J. 2021 Nov 4;58(5):2004168. doi: 10.1183/13993003.04168-2020. PMID: 33863742.
  6. Kheirollahi K, Wasnick R, Biasin V, Vazquez-Armendariz AI, Chu X, Moiseenko A, Weiss A, Wilhelm J, Zhang JS, Kwapiszewska G, Herold S, Schermuly R, Mari B, Li X, Seeger W, Günther A, Bellusci S, El Agha E. Metformin induces lipogenic differentiation in myofibroblasts to reverse mouse and human lung fibrosis; Nat Commun. 2019 Jul 5;10
  7. Schmoldt C Vazquez-Armendariz AI, Shalashova I, Selvakumar B, Bremer CM, Peteranderl C, Wasnick R, Witte B, Gattenloehner S, Fink L, Vadasz I, Morty RE, Pleschka S, Seeger W, Günther A, Herold S, IRE-1 signaling as putative therapeutic target in influenza virus-induced pneumonia; Am J Respir Cell Mol Biol. 2019 Oct;61(4)
  8. Yuan T, Volckaert T, Redente EJ, Yuan J, Chao CM, Wasnick R, Zhang JS, YaoC, Majka S, Stripp B, Günther A, RichesDWH, Bellusci S, Thannickal V and De Langhe SP. Fgf10-Fgfr2b signaling generates basal cells and drives alveolar epithelial regeneration by bronchial epithelial stem cells after lung injury; Stem Cell Reports, 2019 April; pii: S2213-6711(19)30125-0. doi: 10.1016/j.stemcr.2019.04.003.
  9. Klymenko O, Huehn M, Wilhelm J, Wasnick R, Shalashova I, Ruppert C, Henneke I, Hezel S, Guenther K, Mahavadi P, Samakovlis C, Seeger W, Guenther A, Korfei M, Regulation and role of the ER-stress transcription factor CHOP in alveolar epithelial type-II cells; J Mol Med (Berl). 2019 Apr 26. doi: 10.1007/s00109-019-01787-9.
  10. LoehB, Korfei M, Mahavadi P, Wasnick RM, von der Beck D, Guenther A. Pathogenesis. Book chapter in Idiopathic lung fibrosis, Costabel U, Crestani B, Wells AU, ERS Monograph, 2016
  11. MacKenzie B, Korfei M, Henneke I, Sibinska Z, Tian X, Hezel S, Dilai S, Wasnick R, Schneider B, Wilhelm J, El Agha E, Klepetko W, Seeger W, Schermurly R, Guenther A, Bellusci S, Increased FGF1-FGFRc expression in idiopathic pulmonary fibrosis Respir Res. 2015 Jul 3;16:83.
  12. Teisanu RM, Chen H, Matsumoto K, McQualter JL, Potts E, Foster M, Bertoncello I, Stripp BR. Functional analysis of two distinct bronchiolar progenitors during lung injury and repair. Am J Respir Cell Mol Biol. 2011 Jun;44(6):794-803
  13. Teisanu RM, Snyder JC, Stripp BR. Resident stem cells of the lung. Book chapter in Cell Therapy for Lung Disease, Julia Pollack, Imperial College Press, 2010
  14. Teisanu RM, Lagasse E, Whitesides JF, Stripp BR. Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics. Stem Cells. 2009 Mar;27(3):612-22.
  15. Zemke AC, Teisanu RM, Giangreco A, Drake JA, Brockway BL, Reynolds SD, Stripp BR., beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium. Am J Respir Cell Mol Biol. 2009 Feb 12.
  16. Snyder JC, Teisanu RM, Stripp BR. Endogenous lung stem cells and contribution to disease. American Journal of Pathology, 2009 Jan;217(2):254-64.
  17. Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani TJ, Di YP, Taketo MM, Stripp BR. Conditional stabilization of beta-catenin expands the pool of lung stem cells. Stem Cells 2008 May;26(5):1337-46

Roxana Wasnick MD PhD 

Medical Scientist

© Urheberrecht. Alle Rechte vorbehalten.

This webpage contains external links to other websites. The owners are not responsible for the content of these websites.